CD284, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

Search, find, compare suppliers for anti-CD284, Human antibody, protein, ELISA kits.

Edit 
Antigenic SpecificityCD284, Human
CloneHTA125
Host SpeciesMouse
Reactive Specieshuman, other
IsotypeIgG2aκ
Formatbiotin conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCD284 Antibody, anti-human, Biotin. Clone HTA125 reacts with CD284, a type I transmembrane signaling receptor also known as Toll-like receptor 4 (TLR4). Toll-like receptors are a family of pattern recognition receptors detecting the presence and characteristics of an infection and induce appropriately tailored innate and adaptive immune responses. TLR4 associates with its co-receptor MD-2. Together with the lipopolysaccharide (LPS)-binding protein (LBP) and CD14, this complex is responsible for signaling upon LPS recognition. TLR4 is expressed on monocytes and myeloid dendritic cells. Low levels are expressed on B cells and granulocytes in human peripheral blood. HTA125 is able to block LPS-induced signaling and recognizes predominantly human TLR4 associated with MD-2.
Immunogenn/a
Other NamesTLR4, ARMD10, TLR-4, TOLL
Gene, Accession #Gene ID: 7099
Catalog #130-097-349
Price$264
Order / More InfoCD284, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesJin, M. S. and Lee, J-O. (2008) Structures of the toll-like receptor family and its ligand complexes. Immunity 29: 182-191. | Shimazu, R. et al. (1999) MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189: 1777-1782. | Burgener, I. et al. (2008) Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet. Immunol. Immunopathol. 124: 184-191. | Kawahara, T. et al. (2001) Type I Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells. Infect. Immun. 69: 4382-4389. | Wang, J. et al. (2001) Involvement of CD14 and Toll-Like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect. Immun. 69: 2402-2406. | Wang, R. et al. (2003) Characterization of monoclonal antibody HTA125 with specificity for human TLR4. Hybrid. Hybridomics 22: 357-365.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies

© 1980 - 2024 Linscott's Directory, Linscott's USA. All rights reserved.