NGF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNGF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionHedgehog proteins (Hh) are secreted signaling proteins that play many roles during animal development. Aberrant Hh signaling activity can be associated with numerous birth defects and uncontrolled Hh pathway activation is linked to the development of several types of cancers (1-2). The three identified vertebrate Hh genes are Sonic (Shh), Indian (Ihh) and Desert (Dhh), all of which have distinct as well as overlapping roles (3-5). Hh proteins are synthesized as 45 kDa precursors that undergo auto-cleavage to generate a 19 kDa amino-terminal peptide (Hh-N) and a carboxy-terminal peptide (Hh-C). The amino-terminal peptide becomes covalently attached to a cholesterol molecule at its carboxy terminus and acetylated at its amino terminus. This d
ImmunogenImmunogen: A synthetic peptide of human SHH. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[SHH; HHG1; HLP3; HPE3; MCOPCB5; SMMCI; TPT; TPTPS], [SHH; SHH; TPT; HHG1; HLP3; HPE3; SMMCI; ShhNC; TPTPS; MCOPCB5; ShhNp]
Gene, Accession #[NGF], Gene ID: 6469, NCBI: NP_000184.1, UniProt: Q15465
Catalog #MBS857191
Price$290
Order / More InfoNGF Antibody from MYBIOSOURCE INC.
Product Specific References1. Ingham, P.W. and McMahon, A.P. (2001) Genes Dev. 15, 3059-3087. 2. McMahon, A.P. et al. (2003) Curr. Top Dev. Biol. 53, 1-114. 3. Zhang, X.M. et al. (2001) Cell 106, 781-792. 4. Adolphe, C. et al. (2004) Development 131, 5009-5019. 5. Pathi, S. et al. (2001) Mech. Dev. 106, 107-117. 6. Bijlsma, M.F. et al. (2004) Bioessays 26, 387-394.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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