Stat3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityStat3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration500 ug/ml
ApplicationsWestern Blot (WB)
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DescriptionMembrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN alpha and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL 6, it has been shown that Stat3 beta appears to be activated by both while Stat3 alpha is activated by EGF, but not by IL 6. Highest expression of Stat4 is seen in testis and myeloid cells. IL 12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL 3. Stat6 is involved in IL 4 activated signaling pathways.
ImmunogenImmunogen: Stat3 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 73 of rat Stat3 as the immunogen.
Other Names[Rabbit Stat3; Stat3; Stat3; Stat-3; Stat3; Stat 3; Stat-3; Stat 3; Stat-3]
Gene, Accession #[Stat3], Gene ID: 6774, NCBI: AAK17196.1
Catalog #MBS5309118
Price$705
Order / More InfoStat3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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