CREBBP Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CREBBP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CBP (CREB-binding protein) and p300 are highly conserved and functionally related transcriptional co-activators that associate with transcriptional regulators and signaling molecules, integrating multiple signal transduction pathways with the transcriptional machinery (1,2). CBP/p300 also contain histone acetyltransferase (HAT) activity, allowing them to acetylate histones and other proteins (2). Phosphorylation of p300 at Ser89 by PKC represses its transciptional acitivity, and phosphorylation at the same site by AMPK disrupts the association of p300 with nuclear receptors (3,4). Ser1834 phosphorylation of p300 by Akt disrupts its association with C/EBPbeta (5). Growth factors induce phosphorylation of CBP at Ser437, which is required for |
| Immunogen | Immunogen: Recombinant Protein |
| Other Names | [CREB-binding protein isoform b; CREB-binding protein; CREB-binding protein; CREB binding protein] |
| Gene, Accession # | [CREBBP], Gene ID: 1387, NCBI: NP_001073315.1, UniProt: Q92793 |
| Catalog # | MBS9128710 |
| Price | $200, $275, $430 |
| Order / More Info | CREBBP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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