Phospho-RPS6KA1-S363 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-RPS6KA1-S363
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionSerine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upo
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S363 of human RPS6KA1
Other Names[RSK; HU-1; RSK1; p90Rsk; MAPKAPK1A]
Gene, Accession #[RPS6KA1], Gene ID: 6195, NCBI: NP_001006666.1, UniProt: Q15418
Catalog #MBS8550680
Price$280
Order / More InfoPhospho-RPS6KA1-S363 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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