Glutamine Synthetase Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGlutamine Synthetase
Clone[GS-6]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a
Formatunconjugated
Size5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin/Paraffin
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DescriptionGlutamine synthetase (GS) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. GS is present predominantly in the brain, kidneys, and liver. GS in the brain participates in the metabolic regulation of glutamate, the detoxification of brain ammonia, the assimilation of ammonia, recyclization of neurotransmitters, and termination of neurotransmitter signals. In normal liver, GS expression is seen in pericentral hepatocytes, but not in mid-zonal or periportal hepatocytes. GS positive tumor cells are believed to be derived from GS positive hepatocytes. GS immunoreactivity has been seen in a majority of hepatocellular carcinoma (HCC), including cases of
ImmunogenImmunogen: Human Glutamine Synthetase aa. 1-373.
Other Names[glutamine synthetase; Glutamine synthetase; glutamine synthetase; glutamate-ammonia ligase; Glutamate decarboxylase (EC:4.1.1.15); Glutamate--ammonia ligase], [GLUL; GLUL; GS; GLNS; PIG43; PIG59; GLNS; GS]
Gene, Accession #Gene ID: 2752, NCBI: NP_001028228.1
Catalog #MBS370304
Price$130, $205, $240
Order / More InfoGlutamine Synthetase Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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