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Antigenic Specificity | JNK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-alpha and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 412 of human JNK-1 |
Other Names | [JNK1; JNK 1; JNK1,SARP; JNK1A2; JNK; JAK 1A; JAK1A; Stress activated protein kinase], [MAPK8; MAPK8; JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; JNK1; PRKM8; SAPK1; SAPK1C; MAP kinase 8; MAPK 8; SAPK1c] |
Gene, Accession # | [JNK], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
Catalog # | MBS840351 |
Price | $150, $290 |
Order / More Info | JNK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |