MCL-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMCL-1
Clone[8C6; 8C6D4B1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
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DescriptionEntrez Summary: Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysa
ImmunogenImmunogen: Purified recombinant fragment of human MCL-1 expressed in E Coli.
Other Names[EAT; MCL1L; MCL1S], [EAT, MCL1L, MCL1S]
Gene, Accession #[MCL-1], Gene ID: 4170, NCBI: AAF64255.1
Catalog #MBS475660
Price$335
Order / More InfoMCL-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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