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Antigenic Specificity | Rab5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Ras-related protein Rab-5A(RAB5A) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: RAB5A(Ras-associated protein RAB5A), also called RAB5, is a protein that in humans is encoded by the RAB5A gene. RAB5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway. The RAB5A gene is mapped on 3p24.3. Tuberin functions as a RAB5GAP in vivo to negatively regulate RAB5-GTP activity in endocytosis. Ectopically expressed ALS2 localized with RAB5 and early endosome antigen-1 onto early endosomal compartments and stimulated the enlargement of endosomes in cultured cortical neurons. RAB5 is indispensable for a form of receptor |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Rab5 (138-155aa ANKRAVDFQEAQSYADDN), identical to the related rat and mouse sequences. |
Other Names | [Ras-related protein Rab-5A; RAB5A, member RAS oncogene family; RAB 5; RAB 5A; RAB5A; RAB5A member RAS oncogene family; RAB5A_HUMAN; RAS associated protein RAB5A; Ras related protein Rab 5A; Ras-related protein Rab-5A], [RAB5A; RAB5A; RAB5; RAB5] |
Gene, Accession # | [RAB5A], Gene ID: 5868, NCBI: P20339.2, UniProt: P20339 |
Catalog # | MBS175653 |
Price | $315 |
Order / More Info | Rab5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |