Bid Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Bid |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 500 ug/ml |
| Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bid, a BH3 domain containing proapoptotic Bcl 2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces Cytochrome C release and mitochondrial damage. The Cytochrome C releasing activity of Bid was antagonized by Bcl 2. Mutation in the SH3 domain can diminish the Cytochrome C releasing activity. In the animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas. |
| Immunogen | Immunogen: Bid antibody was raised in Rabbit using synthetic peptide surrounding amino acid 37 of human Bid as the immunogen. |
| Other Names | [Rabbit Bid; Bid; Bid] |
| Gene, Accession # | [Bid] |
| Catalog # | MBS5309071 |
| Price | $705 |
| Order / More Info | Bid Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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