BECN1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBECN1
Clone[AT45E8]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1 mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionBeclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene (Atg) 6 and BEC-1 in the C. elegans nematode. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy.
ImmunogenImmunogen: Recombinant human BECN (1-450aa) purified from E. coli
Other Names[beclin 1; ATG6; beclin1; VPS30], [BECN1; BECN1; ATG6; VPS30; beclin1; GT197]
Gene, Accession #[BECN1], Gene ID: 8678, NCBI: NP_003757, UniProt: Q14457
Catalog #MBS200344
Price$240, $315
Order / More InfoBECN1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLiang XH., et al. (1998) J Virol. 72 (11): 8586-8596.; Takacs-Vellai K., et al. (2005) Curr Biol. 15 (16): 1513-1517.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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