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Antigenic Specificity | GAD67 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GAD67 Polyclonal Antibody detects endogenous levels of GAD67 protein. GAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form an |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human GAD67 at AA rangle: 440-520 |
Other Names | [Rabbit GAD67; GAD1; GAD; GAD67; Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform] |
Gene, Accession # | [GAD67], Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259 |
Catalog # | MBS9705077 |
Price | $130, $220, $325 |
Order / More Info | GAD67 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |