Ape1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Ape1 antibody, protein, ELISA kits.
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| Antigenic Specificity | Ape1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ape1 (Apurinic/Apyrimidic eEndonuclease 1), also known as Ref1 (Redox effector factor 1), is a multifunctional protein with several biological activities. These include roles in DNA repair and in the cellular response to oxidative stress. Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway (1). Repair activities of Ape1 are stimulated by interaction with XRCC1 (2), another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, proliferation and differentiation (3). Increased expression of |
| Immunogen | Immunogen: Fusion protein of human APEX1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [APEX1; APE; APE1; APEN; APEX; APX; HAP1; REF1] |
| Gene, Accession # | [Ape1], Gene ID: 328, NCBI: NP_001231178.1, UniProt: P27695 |
| Catalog # | MBS8501849 |
| Price | $310 |
| Order / More Info | Ape1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Demple, B. and Sung, J.S. (2005) DNA Repair (Amst) 4, 1442-9. 2. Vidal, A.E. et al. (2001) EMBO J 20, 6530-9. 3. Tell, G. et al. Antioxid Redox Signal 7, 367-84. 4. Evans, A.R. et al. (2000) Mutat Res 461, 83-108. 5. Olkowski, Z.L. (1998) Neuroreport 9, 239-42. 6. Hayward, C. et al. (1999) Neurology 52, 1899-901. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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