TLR2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR2
Clone[BV31-9]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.03 mL, 0.1 mL
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types are regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.
ImmunogenImmunogen: Recombinant human TLR2
Other Names[Toll-like receptor 2; TLR2; TLR2; CD282; TIL4], [TLR2; TLR2; TIL4; CD282; TIL4]
Gene, Accession #[TLR2], Gene ID: 7097, NCBI: NP_003255.2, UniProt: O60603
Catalog #MBS840028
Price$150, $345
Order / More InfoTLR2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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