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Antigenic Specificity | Mouse IL-17 |
Clone | [4H48] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very r |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of IL-17. |
Other Names | [Il17a; Il17; Ctla8; IL-17; Ctla-8; IL-17A], [Il17a; Il17a; Il17; Ctla8; IL-17; Ctla-8; IL-17A; Ctla8; Il17; IL-17; IL-17A; CTLA-8] |
Gene, Accession # | [IL-17], Gene ID: 16171, NCBI: NP_034682.1, UniProt: Q62386 |
Catalog # | MBS690299 |
Price | $490 |
Order / More Info | Mouse IL-17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |