TTF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTTF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: TTF1 antibody detects endogenous levels of total TTF1. Function: Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.Subunit Structure: Oligomer. The oligomeric structure enables to interact simultaneously with two separate DNA fragments. Interacts with BAZ2A/TIP5. Interacts with CAVIN1.Similarity: The N-terminal region (NRD) inhibits DNA-binding via its interaction with the C-terminal region.
ImmunogenImmunogen: A synthesized peptide derived from human TTF1 Subcellular Location: Nucleus. Nucleus > Nucleolus. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (90%), Horse (90%), Sheep (90%), Rabbit (89%), Dog (90%)
Other Names[RNA polymerase I termination factor; Transcription termination factor 1; Transcription termination factor I; Transcription termination factor RNA polymerase I; TTF 1; TTF-1; TTF-I; Ttf1; TTF1_HUMAN]
Gene, Accession #[TTF1], Gene ID: 7270, NCBI: NP_001192225.1, UniProt: Q15361
Catalog #MBS9609147
Price$240, $280
Order / More InfoTTF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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