Rab5 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Rab5 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Rab5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, monkey, bovine, rat |
| Isotype | n/a |
| Format | ATTO 390 conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: The antibody recognizes 26kDa Rab5 of the above species origins. Scientific Background: Rab5 is a 24kDa member of the Rab family of small guanosine triphosphatases (GTPases), Ras superfamily. Rab GTPases are central regulators of membrane trafficking in the eukaryotic cell. Their regulatory capacity depends on their ability to cycle between the GDP -bound inactive and GTP-bound active states. This conversion is regulated by GDP/GTP exchange factors (GEPs), GDP dissociation inhibitors (GDIs) and GTPase-activating proteins (GAPs) (1, 2). Activation of a Rab protein is coupled to its association with intracellular membranes, allowing it to recruit downstream effector proteins to the cytoplasmic surface of a subcellular compart |
| Immunogen | n/a |
| Other Names | [Rab 5A; RAS associated protein RAB5A; Ras related protein Rab 5 A], [RAB5A; RAB5A; RAB5; RAB5] |
| Gene, Accession # | Gene ID: 5868, NCBI: NP_004153.2, UniProt: Q6FI44 |
| Catalog # | MBS804995 |
| Price | $375 |
| Order / More Info | Rab5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Stenmark H., and Olkkonen V.M. (2001) Genome Biol. 2: 3007.1-3007.7. 2. Takai Y., et al. (2001) Physiol. Rev. 8:, 153-208. 3. Ali B.R., et al. (2004) J. Cell Sci. 117: 6401-6412. 4. Zerial M., and McBride H. (2001) Nat. Rev. Mol. Cell Biol. 2: 107-117. 5. Sonnichsen B., et al. (2000) J. Cell Biol. 149: 901-913 6. Woodman P.G. (2000) Traffic. 1: 695-701.1. Ballmer-Hofer, K., Andersson, A.E., Ratcliffe, L.E. and Berger, P. (2011). Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output. Blood. 118 (3), 816-826. doi: 10.1182/blood-2011-01-328773. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies