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Antigenic Specificity | CD41 |
Clone | [MWReg30] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 kappa |
Format | affinity purified |
Size | 0.05 mg, 0.1 mg |
Concentration | 500 ug/ml |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The MWReg30 monoclonal antibody reacts with mouse CD41. While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and adult. CD41 associates with CD61 to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells. Specifically, it was found that CD150+CD48-bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore |
Immunogen | n/a |
Other Names | [Rat CD41; CD41; CD41; gpIIb/IIIa; CD-41; CD-41; fibrinogen receptor; CD41; CD 41; ITGA2b; CD 41] |
Gene, Accession # | [CD41], NCBI: BAS21495.2 |
Catalog # | MBS5309243 |
Price | $215, $325 |
Order / More Info | CD41 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |