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Antigenic Specificity | KDM3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of HeLa cell line, using KDM3A antibody. KDM3A, also name as JMJD1A, JHDM2A, JMJD1, JMJD1A, KIAA0742 and TSGA, belongs to the JHDM2 histone demethylase family. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It is involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. It is involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1. (PubMed:16603237), JMJD1A is a useful biomarker for hypoxic tumor cells and a prognostic marker that could be a promising therapeutic target agains |
Immunogen | Immunogen: Recombinant protein of human KDM3A |
Other Names | [kdm3a, partial; Kdm3a protein; Kdm3a protein] |
Gene, Accession # | [KDM3A], NCBI: CBJ24782.1 |
Catalog # | MBS4150054 |
Price | $385 |
Order / More Info | KDM3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |