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Antigenic Specificity | Phospho-eIF2 alpha (Tyr150) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, horse, sheep, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-eIF2 alpha (Tyr150) Antibody detects endogenous levels of eIF2 alpha only when phosphorylated at Tyr150. Description: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.Post Translational Modifications: Substrate for at least |
Immunogen | Immunogen: A synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Tyr150. |
Other Names | [EIF 2 alpha; EIF 2; EIF 2A; EIF 2alpha; eIF-2-alpha; eIF-2A; EIF-2alpha; EIF2 alpha; EIF2; EIF2A; EIF2S1; Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa; Eukaryotic translation initiation factor 2 subunit 1 alpha; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; IF2A_HUMAN] |
Gene, Accession # | [eIF2 alpha], Gene ID: 1965, NCBI: NP_004085.1, UniProt: P05198 |
Catalog # | MBS9610550 |
Price | $225, $280, $340 |
Order / More Info | Phospho-eIF2 alpha (Tyr150) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |