IGF2R Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIGF2R
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionThis gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).
ImmunogenImmunogen: Recombinant protein of human IGF2R
Other Names[CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR 300; MPR1; MPR300; MPRI]
Gene, Accession #[IGF2R], Gene ID: 3482, NCBI: P11717.3, UniProt: P11717
Catalog #MBS9131230
Price$275, $430, $655
Order / More InfoIGF2R Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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