VDAC1/Porin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVDAC1/Porin
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionForms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
ImmunogenImmunogen: A synthesized peptide derived from human VDAC1. Subcellular Localization: Mitochondrion outer membrane. Cell membrane. Tissue Specificity: Heart, liver and skeletal muscle.
Other Names[Voltage-dependent anion-selective channel protein 1; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC1; VDAC], [VDAC1; VDAC1; PORIN; VDAC-1; VDAC; VDAC-1; hVDAC1]
Gene, Accession #[VDAC1], Gene ID: 7416, NCBI: NP_003365.1, UniProt: P21796
Catalog #MBS179576
Price$160, $340, $340
Order / More InfoVDAC1/Porin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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