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Antigenic Specificity | CBX1 (C-term), 128-155 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the C-terminal region of human CBX1. CBX1 is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. |
Immunogen | n/a |
Other Names | [Chromobox protein homolog 1; HP1Hsbeta; Heterochromatin protein 1 homolog beta; HP1 beta; Heterochromatin protein p25; M31; Modifier 1 protein; p25beta; CBX1; CBX] |
Gene, Accession # | [CBX1], Gene ID: 10951, NCBI: NP_001120700.1, UniProt: P83916 |
Catalog # | MBS9203619 |
Price | $165, $370 |
Order / More Info | CBX1 (C-term), 128-155 Antibody from MYBIOSOURCE INC. |
Product Specific References | Aagaard,L., et.al., EMBO J. 18 (7), 1923-1938 (1999) |