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Antigenic Specificity | IFIT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of IFIT2 protein. IFIT2 (Interferon Induced Protein With Tetratricopeptide Repeats 2) is a Protein Coding gene. Among its related pathways are Type II interferon signaling (IFNG) and Interferon gamma signaling. IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2-O-methylation of the 5 cap. The ribose 2-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2-O-methylase for their mRNAs or by stealing host cap containing the 2-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or w |
Immunogen | Immunogen: Synthesized peptide derived from part region of human IFIT2 protein at amino acid sequence of 200-280 |
Other Names | [Rabbit IFIT2; Interferon-induced protein with tetratricopeptide repeats 2; IFIT-2; ISG-54 K; Interferon-induced 54 kDa protein; IFI-54K; P54] |
Gene, Accession # | [IFIT2], Gene ID: 3433, NCBI: NP_001538.4, UniProt: P09913 |
Catalog # | MBS9709449 |
Price | $130, $220, $325 |
Order / More Info | IFIT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |