TIA-1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TIA-1 |
| Clone | [ABM47E1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.025 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TIA1 (T-cell intracellular antigen) are mRNA-binding proteins that can aggregate within granules under specific stress conditions. TIA-1 is a multi-domain ribonucleic acid (RNA) binding protein that recognizes poly-uridine tract RNA sequences to facilitate 5'splice site recognition by the U1 small nuclear ribonucleoprotein (snRNP). TIA1 mutation causes perturbed RNA splicing and cellular stress resulting in WDM (Welander distal myopathy). TIA-1 regulates developmental and stress-responsive pathways through distinct activities at the levels of alternative pre-mRNA splicing and mRNA translation by recognising uridine-rich sequences of RNAs. |
| Immunogen | Immunogen Information: A partial length recombinant TIA-1 protein (amino acids 182-385) was used as the immunogen for this antibody. |
| Other Names | [TIA1; RNA-binding protein TIA-1; TIA-1; T-cell-restricted intracellular antigen-1; p40-TIA-1; to TIA-1; TIA-1; TIA-1], [TIA1; TIA1; WDM; TIA-1; TIA-1] |
| Gene, Accession # | [TIA1], Gene ID: 7072, NCBI: P31483.3, UniProt: P31483 |
| Catalog # | MBS668467 |
| Price | $145, $290 |
| Order / More Info | TIA-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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