Edit |   |
---|---|
Antigenic Specificity | Versican |
Clone | [S351-23] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects >350 kDa. Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a Lectinlike sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length anddegree of modification by glycoaminoglycan chains. Accumulation around smooth muscle cells in lesions of athero-sclerosis suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tu |
Immunogen | Immunogen: Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein |
Other Names | [Mouse Mouse Versican IgG1; Versican : APC/Cy7; Chondroitin sulfate proteoglycan 2; CSPG2; ERVR; GHAP; PG-M; VCAN; Chondroitin sulfate proteoglycan 2; Chondroitin sulfate proteoglycan core protein 2; Glial hyaluronate binding protein; Glial hyaluronate-binding protein; Large fibroblast proteoglycan; Large fibroblast proteoglycan; PGM; V1 Neo; Versican core protein; Versican proteoglycan; Versican V0; WGN 1; WGN; WGN1] |
Gene, Accession # | [VCAN], Gene ID: 13003, NCBI: Q62059.2, UniProt: Q62059 |
Catalog # | MBS8003328 |
Price | $510 |
Order / More Info | Versican Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Dours-Zimmermann M.T. and Zimmermann D.R. (1994) J. Biol. Chem. 52: 32992-32998. 2. Evanko S.P., Angello J.C. and Wight T.N. (1999) Arterioscler. Thromb. Vasc. Biol. 4:1004-1013. 3. Lemire J.M., et al. (1999) Arterioscler. Thromb. Vasc. Biol. 7: 1630-1639. 4.Wight T.N. (2002) Curr. Opin. Cell Biol. 5: 617-623. 5. Touab M., Villena J., Barranco C., Arumi-Uria M. and Bassols A. (2002) Am. J. Pathol. 2: 549-557. |