GluN1/NR1 NMDA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGluN1/NR1 NMDA
Clone[S308-48]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatAPC-Cy7 conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionDetects ~105 kDa. The NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controlling synaptic plasticity and memory function (1). The NMDA receptor forms a heterotetramer between two NR1 and two NR2 subunits (the subunits are also called glutamate-binding NMDA receptor subunits or GluN for short); two obligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunits have an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits.
ImmunogenImmunogen: Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1
Other Names[Mouse Rat GluN1/NR1 IgG1; GluN1/NR1 : APC/Cy7; NMDAR1; NMDA Receptor 1; NMDAR; NMDA1; GRIN1; Glutamate [NMDA] receptor subunit zeta-1; Glutamate receptor ionotropic N methyl D aspartate 1; MRD8; N methyl D aspartate receptor; N methyl D aspartate receptor channel subunit zeta 1; N methyl D aspartate receptor subunit NR1; NMD-R1; NMDA 1; NMDA R1; NMDZ1_HUMAN; NR1; GluN1]
Gene, Accession #[GluN1], Gene ID: 24408, NCBI: NP_001257531.1, UniProt: P35439
Catalog #MBS8003154
Price$510
Order / More InfoGluN1/NR1 NMDA Antibody from MYBIOSOURCE INC.
Product Specific References1. Li F., and Tsien J.Z. (2009) New England J. Medicine. 361: 302-303. 2. Garcia-Gallo M., Renart J., Diaz-Guerra M. (2001) Biochem J. 356: 539-547. 3. Atlason P.T., Garside M.L., Meddows E., Whiting P., McIllhinney R.A.J. (2007) J Biol Chem. 282(35): 25299-25307.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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