Bid Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBid
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formation exchange purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionBid Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize.
ImmunogenImmunogen: Bid antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bid. Buffer: Bid Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Bid; FP497; BH3-interacting domain death agonist; p22 BID; BID; BH3 interacting domain death agonist], [BID; BID; FP497; BID]
Gene, Accession #[BID], Gene ID: 637, NCBI: AAH36364, UniProt: P55957
Catalog #MBS150537
Price$375
Order / More InfoBid Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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