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Antigenic Specificity | Phospho-Ser129 Alpha Synuclein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~15 kDa alpha-synuclein protein phosphorylated at Ser129. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser129 of alpha synuclein. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser129 conjugated to KLH. Immunogen Species: Rat |
Other Names | [alpha-synuclein; Alpha-synuclein; alpha-synuclein; synuclein, alpha (non A4 component of amyloid precursor)], [Snca; Snca] |
Gene, Accession # | [SNCA], Gene ID: 29219, NCBI: NP_062042.1, UniProt: P37377 |
Catalog # | MBS502004 |
Price | $360 |
Order / More Info | Phospho-Ser129 Alpha Synuclein Antibody from MYBIOSOURCE INC. |
Product Specific References | • Okochi M, Walter J, Koyama A, Nakajo S, Baba M, Iwatsubo T, Meijer L, Kahle PJ, Haass C (2000) Constitutive phosphorylation of the Parkinson's disease associated alphasynuclein. J Biol Chem Jan 7;275(1): 390-7.• Neumann M, Kahle PJ, Giasson BI, Ozmen L, Borroni E, Spooren W, Muller V, Odoy S, Fujiwara H, Hasegawa M, Iwatsubo T, Trojanowski JQ, Kretzschmar HA, Haass C (2002) Misfolded proteinase k resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha synucleinopathies. J Clin Invest Nov; 110(10):1403-5.• Smith WW, Margolis RL, Li X, Troncoso JC, Lee MK, Dawson VL, Dawson TM, Iwatsubo T, Ross CA (2005) Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y Cells. J Neurosci June 8; 25(23):5544-5552.• Masliah E, Rockenstein E, Adame A, Alford M, Crews L, Hashimoto M, Suebert P, Lee M, Goldstein J, Chilcote T, Games D, Schenk D (2005) Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease. Neuron Jun 16;46(6):857-868. |