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Antigenic Specificity | Nogo Receptor (Nogo-R, Reticulon Receptor 4, NgR1, Nogo-66 Receptor) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Nogo receptor is a leucine-rich repeat (LRR) containing protein with a glycosylphosphatidylinositol (GPI) anchored C-terminus. The receptor was identified on the basis of its ability to bind with high affinity to Nogo-A a member of the reticulon family expressed in the cell membrane of oligodendrocytes.1 Nogo-A attracted attention when it was demonstrated that it is a myelin protein capable of inhibiting axonal growth following nerve injury.2, 3 Other myelin proteins also identified as axonal growth inhibitors are the myelin-associated glycoprotein (MAG) a sialic-dependent immunoglobulin-like family member lectin (SIGLEC) and the oligodendrocyte myelin glycoprotein (OmgP) which is a GPI-anchored membrane protein. Remarkably, despite the |
Immunogen | Immunogen: Peptide (C)GDSPPGNGSGPRHIND corresponding to amino acid residues 366-381 of the human Nogo receptor (Accession Q9BZR6). |
Other Names | [Nogo receptor; reticulon-4 receptor; reticulon 4 receptor] |
Gene, Accession # | [NOGO-R], Gene ID: 65078 |
Catalog # | MBS4157665 |
Price | $725 |
Order / More Info | Nogo Receptor (Nogo-R, Reticulon Receptor 4, NgR1, Nogo-66 Receptor) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |