Phospho-ERK 1/2 (Tyr222/205) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-ERK 1/2 (Tyr222/205) |
| Clone | [4D4] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | 1mg/mL |
| Applications | Immunohistochemistry (IHC) Paraffin (IHC-p) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity. |
| Immunogen | Immunogen: Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205) Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 Conjugation: Unconjugated |
| Other Names | [MAPK1/MAPK3] |
| Gene, Accession # | [ERK 1/2], Gene ID: 5595, NCBI: NP_001035145.1, UniProt: P27361 |
| Catalog # | MBS2549858 |
| Price | $110, $150, $225 |
| Order / More Info | Phospho-ERK 1/2 (Tyr222/205) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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