Chk1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityChk1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionChk1 is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis.
ImmunogenImmunogen: Chk1 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of serine 280 (V-T-S(p)-G-G) derived from Human Chk1 as the immunogen.
Other Names[Rabbit Chk1; Chk1; Chk1; Chk1; Chk 1; CHEK1; Chk-1; Chk-1; Phospho Ser280; Chk 1]
Gene, Accession #[Chk1], Gene ID: 1111, NCBI: AAC51736.1
Catalog #MBS5309541
Price$295
Order / More InfoChk1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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