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Antigenic Specificity | Src |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Src (phospho-Tyr529) antibody detects endogenous levels of Src only when phosphorylated at tyrosine 529. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. This gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Src around the phosphorylation site of tyrosine 529 (P-Q-YP-Q-P). |
Other Names | n/a |
Gene, Accession # | [Src] |
Catalog # | MBS417444 |
Price | $325 |
Order / More Info | Src Antibody from MYBIOSOURCE INC. |
Product Specific References | Pyper J.M., (1985) Mol. Cell. Biol. 5:831-838Pyper J.M.(1990) Mol. Cell. Biol. 10:2035-2040Xu W., (1997).Nature 385:595-602Benes C.H., (2005) Cell 121:271-280 |