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Antigenic Specificity | Human TLR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~75-80kD when tested against partial recombinant mouse TLR4 (extracellular portion plus His-tag). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. |
Immunogen | Immunogen Description: Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4. |
Other Names | [TLR4 (aa420-435) IHC-plus; TLR4; CD284; CD284 antigen; Homolog of Drosophila toll; TLR-4; TOLL; ARMD10; Toll-like receptor 4; HToll; Human TLR4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206 |
Catalog # | MBS242878 |
Price | $530 |
Order / More Info | Human TLR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |