CD257/BAFF/TNFSF13B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD257/BAFF/TNFSF13B
Clone[C257/1638]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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DescriptionSpecificity: BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
ImmunogenImmunogen: Purified recombinant human full-length CD257 protein. Cellular Localization: Cell Surface and Cytoplasmic
Other Names[ApoL related ligand TALL 1; B lymphocyte stimulator; B-cell-activating factor; BAFF; BLyS; CD257; Dendritic cell-derived TNF-like molecule; DTL; PRO738; TALL-1; THANK; TNFSF13B; TNFSF20; Tumor necrosis factor ligand superfamily member 13b; Tumor necrosis factor ligand superfamily member 20; ZTNF4], [BAFF; TNFSF13B]
Gene, Accession #[CD257], Gene ID: 10673, NCBI: NP_001139117.1, UniProt: Q9Y275
Catalog #MBS439850
Price$190, $340, $340
Order / More InfoCD257/BAFF/TNFSF13B Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSchneider P, et al. 1999. J. Exp. Med. 189:1747. Moore PA, et al. 1999. Science 285:260.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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