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Antigenic Specificity | Neurofilament, phospho (NF-H) (Neuronal Marker) |
Clone | [NE14] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, guinea pig, Gerbil, cat, porcine, rabbit, cow, chicken |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). It reacts specifically with the phosphorylated KSP/KEP segment at the C-terminus of the heavy subunit (NF-H) of neurofilaments. After dephosphorylation of neurofilaments with alkaline phosphatase, this Ab no longer binds. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neurobla |
Immunogen | Immunogen: Crude neurofilament preparation from porcine spinal cord |
Other Names | [NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200], [NEFH; NEFH; NFH; CMT2CC; KIAA0845; NFH; NF-H] |
Gene, Accession # | [NEFH], Gene ID: 4744, NCBI: NP_066554.2, UniProt: P12036 |
Catalog # | MBS439297 |
Price | $190, $340, $340 |
Order / More Info | Neurofilament, phospho (NF-H) (Neuronal Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Debus E., et al. Differentiation 25(2), 193-203 (1983). Gotow T., et al. J. Neuroscience Res. 37(6), 691-713 (1994). Berglund A.M., et al. J Comp Neurol. 306(3), 393-408 (1991). Guadano-Ferraz A., et al. Develop. Brain Res. GOTOBUTTON BM_4_ 56(2), 244-256, (1990). Obermann W., et al. Eur. J. Biochem 233, 110-115 (1995). Marx A., et al. Am. J.Pathol. 148(6), 1839-1850 (1996) |