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Antigenic Specificity | Phospho-MAPK14-T180 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T180 of human MAPK14 Calculated Molecular Weight: 43kDa |
Other Names | [Phospho-MAPK14-T180: MAPK2; MAPKAPK-2; MAPKAPK2], [MAPK14; MAPK14; RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; MAP kinase 14; MAPK 14; CSAID-binding protein; CSBP; MAP kinase p38 alpha; SAPK2a] |
Gene, Accession # | [MAPK14], Gene ID: 1432, NCBI: Q16539.3, UniProt: Q16539 |
Catalog # | MBS128230 |
Price | $235, $350, $525 |
Order / More Info | Phospho-MAPK14-T180 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |