SETD2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySETD2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.7 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total SETD2 protein. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human SET domain containing 2
Other Names[HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP]
Gene, Accession #[SETD2], Gene ID: 29072, NCBI: NP_054878.5, UniProt: Q9BYW2
Catalog #MBS9408796
Price$255
Order / More InfoSETD2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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