Phospho- JNK/SAPK (pThr183/pTyr185) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho- JNK/SAPK (pThr183/pTyr185)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, chicken, bovine dog
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes human JNK protein. It also reacts with rat and mouse JNK protein. The other species are not tested. c-Jun N-terminal Kinase (JNK) is a Stress Activated Protein Kinase/Map Kinase (SAPK/MAPK). There are three isoforms, JNK1 (~49 kDa), JNK2 (~55 kDa), and JNK3 (~54 kDa). JNK is dually phosphorylated at Thr 183 and Tyr 185 by protein kinases MKK4 and MKK7. The JNK and p38 pathways function to modulate cell-cycle, apoptotic and transcriptional responses to stress.
ImmunogenAntigen Preparation: A synthetic peptide surrounding to the epitope -TPY- with dual phosphorylation sites at Thr183 and Tyr185 of human JNK/SAPK.
Other Namesn/a
Gene, Accession #[JNK/SAPK1 (pT183/pY185)]
Catalog #MBS462109
Price$285
Order / More InfoPhospho- JNK/SAPK (pThr183/pTyr185) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYogev,O., et al. DNA damage-dependent translocation of B23 and p19 ARF is regulated by the Jun N-terminal kinase pathway. Cancer Res. 68 (5), 1398-1406 (2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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