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Antigenic Specificity | Myelin Basic Protein |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myelin basic protein is reported to account for about 30 of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity; though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves, though it is expressed less abundantly in gray mat |
Immunogen | Immunogen: Mixture of 3 MBP peptides which are the different forms of the protein which are alternate transcription from a single gene. |
Other Names | [Myelin basic protein; Myelin basic protein; Golli-MBP; myelin basic protein; myelin basic protein; Myelin A1 protein; Myelin membrane encephalitogenic protein], [MBP; MBP; MBP] |
Gene, Accession # | Gene ID: 4155, NCBI: P02686.3 |
Catalog # | MBS555038 |
Price | $380 |
Order / More Info | Myelin Basic Protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |