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Antigenic Specificity | CD41 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous human CD41/ Intergrin alpha2b protein. ITGA2B encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. Integrin subunit alpha 2b plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in ITGA2B are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Mouse CD41; ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41] |
Gene, Accession # | [CD41], Gene ID: 3674, NCBI: NP_000410.2, UniProt: P08514 |
Catalog # | MBS9700388 |
Price | $130, $220, $325 |
Order / More Info | CD41 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |