Bcl-XL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBcl-XL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.50ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionAffinity Purified Bcl-2-like protein 1 Antibody. Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 150-200 on human BCL-2-like protein 1. Immunoglobulin: IgG. Expression: Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Other Names[Apoptosis regulator Bcl X; B cell lymphoma 2 like; B2CL1_HUMAN; Bcl 2 like 1 protein; Bcl X; Bcl xL; BCL XL/S; Bcl xS; Bcl-2-like protein 1; Bcl2 Like 1; Bcl2 related gene; BCL2L; BCLX; PPP1R52; Protein phosphatase 1 regulatory subunit 52], [BCL2L1; BCL2L1; BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S; BCL2L; BCLX; Bcl2-L-1]
Gene, Accession #[Bcl-XL], Gene ID: 598, NCBI: Q07817.1, UniProt: Q07817
Catalog #MBS541042
Price$390
Order / More InfoBcl-XL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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