PERK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPERK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration1mg/mL
ApplicationsImmunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA)
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DescriptionPhosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
ImmunogenImmunogen: Synthesized peptide derived from human PERK around the non-phosphorylation site of Thr981. Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 Conjugation: Unconjugated
Other Names[EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK]
Gene, Accession #[PERK], Gene ID: 9451, NCBI: NP_004827.4, UniProt: Q9NZJ5
Catalog #MBS2549195
Price$110, $150, $225
Order / More InfoPERK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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