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Antigenic Specificity | NGF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of mouse liver tissue, using NGF antibody. Nerve growth factor (NGF) is a small, secreted protein and member of the neurotrophin family of growth factors that promote neuronal cell survival and differentiation (1). Producing cells release NGF that bind and activate TrkA high affinity receptors to mediate NGF-driven signaling. NGF also binds to a low affinity p75 (NTR) receptors, which belong to the death receptor family (2). Although NGF has been classically described as favoring neuron survival and differentiation, nerve growth factor can promote apoptosis in cells that contain p75 (NTR) and lack TrkA. NGF can induce neuron death in a variety of neurodegenerative conditions, including Alzheime |
Immunogen | Immunogen: A synthetic peptide of human NGF |
Other Names | [NGF, partial; Beta-nerve growth factor; beta-nerve growth factor; nerve growth factor], [NGF; NGF; NGFB; HSAN5; Beta-NGF; NGFB; Beta-NGF] |
Gene, Accession # | [NGF], Gene ID: 4803, NCBI: AKI72032.1 |
Catalog # | MBS419414 |
Price | $385 |
Order / More Info | NGF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |