GluA1/GluR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGluA1/GluR1
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoblot (IB)
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DescriptionThis antibody recognizes mouse and rat GluA1/GluR1. It does not cross-react with GluR2. Regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) plays a key role in altering excitatory synaptic transmission in the CNS. Interestingly, the regulatory mechanisms differ between distinct subunits of AMPAR, which range from glutamate receptor 1 (GluR1) to GluR4 (also referred to as GluA1-4). For example, subunits with a long intracellular carboxy terminus (i.e., GluR1, GluR2L, and GluR4) are involved in activity-dependent synaptic targeting of AMPAR, whereas those with a shorter carboxy terminus (i.e., GluR2, GluR3, and GluR4s) seem to maintain basal synaptic transmission. GluR1 has several phosphorylation sites
ImmunogenAntigen: Fusion protein corresponding to aa 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (accession no. P19490).
Other Names[GluA1/GluR1], [GRIA1; GRIA1; GLUH1; GLUR1; GLURA; GluA1; HBGR1; GLUH1; GLUR1; GluR-1; GluA1]
Gene, Accession #[GluA1/GluR1], Gene ID: 2890, NCBI: NP_000818.2
Catalog #MBS190931
Price$410
Order / More InfoGluA1/GluR1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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