CD253/TRAIL/ (TNFSF10) (IN1) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD253/TRAIL/ (TNFSF10) (IN1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody recognizes ~~34 kDa of human TRAIL protein. The TRAIL (TNF related apoptosis induced ligand) or Apo 2L /CD253 protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. The ligand binding to its receptors DR4/DR5 initiates apoptosis of tumor cells. TRAIL is expressed predominantly in spleen, lung, and prostate but also in many other tissues. TRAIL is a type II membrane protein from the TNF family. The human form of the protein is 281 amino acids in length, whereas the murine form is 291 amino acids. The two forms share 65% identity. TRAIL protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a
Immunogenn/a
Other Namesn/a
Gene, Accession #[CD253/TRAIL], Gene ID: 8743
Catalog #MBS460360
Price$270
Order / More InfoCD253/TRAIL/ (TNFSF10) (IN1) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPitti, R.M., Marsters, S.A., Ruppert, S., Donahue, C.J., Moore, A. and Ashkenazi, A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271 (22), 12687-12690 (1996)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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