PKM2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PKM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PKM2 (pyruvate kinase M2), its association with phospho-tyrosine (pTyr) motifs, enables cells to use predominantly aerobic glycolysis instead of oxidative phosphorylation. Also this change may benefit cancer cells by enabling them to redirect glycolytic metabolites away from oxidation and energy production and, instead, toward anabolic processes and biosynthesis. PKM2-mediated generation of the aerobic glycolytic phenotype, although wasteful in terms of glucose consumption and waste generation, could provide a variety of advantages for cancerous cells. In addition nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death. |
| Immunogen | Immunogen: PKM2 antibody was raised in Rabbit using the peptide sequence around aa 36~40(D-S-P-P-I) derived from Human PKM2 as the immunogen. |
| Other Names | [Rabbit PKM2; PKM2; PKM2; PK2; PKM 2; PKM; Pyruvate kinase muscle; Pyruvate kinase isozymes M1/M2; PKM2; THBP1; CTHBP; Pyruvate kinase 2/3; M2-PK; p58; PKM-2; Tumor M2-PK; PKM2; PKM 2; PKM-2; TCB; PKM; OPA interacting protein 3; Thyroid hormone binding protein cytosolic; pyruvate kinase; muscle isoform M2 OIP3; PK3; Cytosolic thyroid hormone binding protein] |
| Gene, Accession # | [PKM2] |
| Catalog # | MBS5309828 |
| Price | $295 |
| Order / More Info | PKM2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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