Chk1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Chk1 |
| Clone | [2G1D2] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human, mouse and rat Chk1. Detects a band of ~55kDa by Western blot. The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)induced degradation of cdc25A. |
| Immunogen | Immunogen: Recombinant human Chk1. |
| Other Names | [Chk1], [CHEK1; CHEK1; CHK1; CHK1] |
| Gene, Accession # | [Checkpoint kinase 1], Gene ID: 1111, NCBI: O14757.2, UniProt: O14757 |
| Catalog # | MBS565097 |
| Price | $345 |
| Order / More Info | Chk1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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