Phospho-ERK3 (Ser189) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-ERK3 (Ser189)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-ERK3 (Ser189) Antibody detects endogenous levels of ERK3 only when phosphorylated at Ser189. Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).Post Translational Modifications: Phosphorylated at Ser-189 by PAK1, PAK2 and PAK3 resulting in catalytic activation. Phosphorylated by MAPKAPK5 at oth
ImmunogenImmunogen: A synthesized peptide derived from human ERK3 around the phosphorylation site of Ser189. Tissue Specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
Other Names[ERK-3; ERK3; Extracellular signal regulated kinase 3; Extracellular signal regulated kinase p97; Extracellular signal-regulated kinase 3; HsT17250; MAP kinase 6; MAP kinase isoform p97; MAPK 6; MAPK6; Mitogen activated protein kinase 6; Mitogen-activated protein kinase 6; MK06_HUMAN; p97 MAPK; p97-MAPK; PRKM6; Protein kinase mitogen activated 5; Protein kinase mitogen activated 6]
Gene, Accession #[ERK3], Gene ID: 5597, NCBI: NP_002739.1, UniProt: Q16659
Catalog #MBS9610769
Price$225, $280, $340
Order / More InfoPhospho-ERK3 (Ser189) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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