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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti fungal response, while the related 18 wheeler is involved in antibacterial defenses. TLR4 has been identified next to MD2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram negative bacteria. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. |
Immunogen | Immunogen: Synthetic peptide from the N-terminal region of human TLR4, conjugated to KLH. Preservative: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4. Cellular Localization: Plasma membrane |
Other Names | [Mouse IgG to TLR4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10] |
Gene, Accession # | [TLR4], Gene ID: 7099, NCBI: NP_612564.1, UniProt: O00206 |
Catalog # | MBS850461 |
Price | $215, $280 |
Order / More Info | TLR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |